Journal: Neurology: Genetics
Article Title: DMPK mRNA Expression in Human Brain Tissue Throughout the Lifespan
doi: 10.1212/NXG.0000000000000537
Figure Lengend Snippet: Fitted values for normalized DMPK expression (y-axis) in the human brain throughout the lifespan (x-axis). The curves represent the fitted values derived from restricted cubic spline model with normalized DMPK expression was predicted by age. Panel A (left) shows results from BrainSpan database messenger RNA sequencing method; panel B (right) shows results from Yale database microarray method. DMPK = myotonic dystrophy protein kinase; PCW = postconceptional week.
Article Snippet: Detailed methods have been previously described, and the Yale Microarray RNA-sequencing data for this analysis was accessed from the National Center for Biotechnology Information (NCBI) Gene Expression Omnibus (GEO; GEO accession number GSE25219; ncbi.nlm.nih.gov/geo ).
Techniques: Expressing, Derivative Assay, RNA Sequencing, Microarray